What’s the Best Medicine for Arthritis Pain


Have you ever experienced waking up in the morning and not being able to open your hands or move your fingers? Have you ever experienced feeling as if your joints are swollen and inflamed so that when you touch them, they hurt? If you have experienced this at some point in your life, you may have arthritis.

Arthritis is one of the most common conditions experienced by people of all ages all over the world. Anywhere in the world, someone suffers from it. This joint disorder or joint disease is often misunderstood. Arthritis is not just one disease or condition; it pertains to over a hundred of arthritis or arthritis-related conditions.

A person who has arthritis experiences different symptoms. The most common ones are a pain, swelling, decreased the range of motion, and stiffness. These symptoms normally stay for several hours or days, and they can be mild or moderate, or quite severe. In some cases, arthritis symptoms become worse as years go on. If this happens, a person will not be able to function normally as it becomes tough to move without feeling the pain (which has become chronic).

Different factors cause arthritis. One that is caused by injury can lead to osteoarthritis, while one that is caused by a weakened immune system can be rheumatoid arthritis or systematic lupus erythematosus. There are specific arthritis types, though: degenerative arthritis (osteoarthritis), inflammatory arthritis, metabolic arthritis (uric acid), and infectious arthritis.

Because of the pain and discomfort that comes with arthritis, it is often considered a disease, one that can affect even children.

One of the most common characteristics of arthritis is inflammation, particularly of the joints. This is what makes the disease inconvenient and difficult. People living with Arthritis must deal with a lot of pain and inflammation, and doing so will often interfere with their daily activities. This is where the best medicines for arthritis pain come in.

Aside from physical therapy, doctors always prescribe pain medication, anti-inflammatory drugs, and other medications. What he or she gives is dependent on the type and level of arthritis you have.

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Who Needs Arthritis Medicine?

People who have any arthritis are the ones who need the right arthritis medicine. It is essential to first consult with a rheumatologist before taking any medication to be sure that what you are experiencing is arthritis or symptoms related to it.

Arthritis does not choose any age or gender. Men, women, young, and old – anyone can develop arthritis. So, children with arthritis can also take medication prescribed by the doctor.

What is Arthritis Medicine?

The best medicines for arthritis pain help people manage their symptoms. These medications are intended to alleviate swelling, inflammation, stiffness, and of course, joint pain. Most arthritis medicines are formulated to relieve pain, but there are quite a few that can also heal and repair.

However, it is important to note that there are different medication options to choose from. Moreover, what you choose or will be prescribed to you will depend on your doctor. A rheumatologist decides from several arthritis medicine classes. The most common ones are acetaminophen, corticosteroids, NSAIDS, DMARDS, and Biologics. Each of these medications has their characteristics and ingredients.

Aside from medicines, arthritis pain and symptoms can also be alleviated by certain lifestyle changes, particularly diet and exercise. Your doctor may also recommend you undergo therapy.

The ideal diet for someone who has arthritis is one that includes nutrient-rich food, especially one that is good for the joint. A perfect example for this is all the food on a Mediterranean diet, which means olive oil, nuts and seeds, beans, fish, whole grains, and fruits and vegetables.

Exercise is also essential, although you do not have to do that high intensity, complicated ones. It is best if you consult with your doctor and then with a professional fitness trainer before starting an exercise routine. Yoga, walking, stretching exercises, and light aerobic dancing are some excellent examples of workouts you can do.

Staying physically active is essential in ensuring proper arthritis management.

Additionally, weight is a significant factor. So as much as possible, move around. Make sure that you stand up and stretch once in awhile. Also, do not overstress your joints. Learn to rest and relax.

Lastly, all your arthritis medication will not do any good if you do not go for regular check-ups with your rheumatologist.

What are the components of Arthritis Medicine?

As previously mentioned, there are several types or classifications of arthritis medicine. Each one is intended for a condition or symptom. Choosing and finding the best medicines for arthritis pain will be easier if you know what you need.

Here are the most common arthritis medications:

Acetaminophen. This medication can be one of the best medicines for arthritis pain. It is used for managing pain caused by arthritis. It is available over-the-counter and does not need a prescription from the doctor. However, it is still important to inform your doctor if you plan to take acetaminophen for managing arthritis pain to make sure you will not have adverse reactions or allergies to it.

An example of an acetaminophen is Tylenol.

Corticosteroid. These are steroid medications that help control and reduce inflammation. They are usually prescribed for people with rheumatoid arthritis and osteoarthritis. These, however, need doctor’s prescription and cannot be bought over-the-counter.

Examples include Medrol and Deltasone.

NSAIDS. NSAIDS or nonsteroidal anti-inflammatory drugs help reduce pain and relieve inflammation caused by arthritis and other similar or related conditions. Many people also use NSAIDs in managing symptom flare-ups. These medicines for arthritis are available over-the-counter and come in different varieties: aspirin, ibuprofen, and naproxen. NSAIDs can be the best medicines for arthritis pain because they can alleviate symptoms, but they are known to have many side effects including risk of blood clots, stomach ulcer, gastrointestinal tract bleeding, increased stroke and heart attack risk, and kidney damage.

DMARDS. DMARDs are Disease-Modifying Anti-Rheumatic Drugs. They are intended for alleviating pain, and symptoms cause by rheumatoid arthritis and autoimmune conditions. DMARDs work by controlling the immune system reactions. However, like NSAIDS, they can cause specific side effects, such as a decrease in the production of red blood cells; damage to lungs, stomach, mouth, and intestines; and liver damage.

Biologics. These are genetically-engineered/synthetic oral drugs and care for people living with rheumatoid arthritis. Biologics have not been around for a long time; the first one came out in 1998 (Enbrel/etanercept). The best medicines for arthritis pain target parts of the immune system that are responsible for causing inflammation. Other examples are Orencia/abatacept, Humira/adalimumab, and Remicade/infliximab.

Counterirritants. These are creams and ointments that you can rub or apply on your skin to help lessen joint pain. Counterirritants usually contain capsaicin (which is used in adding spice to hot peppers) or menthol.

Choosing the right arthritis medication is essential to achieving the desired results.

What are the Precautions of Arthritis Medicine?

Even the best medicines for arthritis pain can have side effects. As such, it is important to exercise precaution.

Some of the side effects you need to watch out for are as follows:

For acetaminophens – dizziness, nausea, constipation, vomiting, and lightheadedness for prescription-strength acetaminophens. Non-prescription acetaminophens have no side effects when taken as directed. Taking in more than the prescribed dosage, however, can lead to liver damage. It will also help if you consult with your doctor before taking acetaminophen (or any arthritis medicine) to make sure that it will not react with whatever other medication you are seeking.

For corticosteroids – bone loss, cataracts, increase blood sugar levels and elevated levels of blood fats.

For NSAIDS – edema, stomach upset, possible increased blood clots risk, stomach ulcers, increased risk of stroke and heart attack, heartburn.

For DMARDS – increased susceptibility to infections, and stomach upset. Some brands have certain side effects, too.

For biologics – when biologics are injected, one can develop an adverse or adverse reaction to the injection such as swelling and redness; nausea, rapid/weak pulse, vomiting, and difficulty in breathing.

All these side effects can be prevented and managed if you consult with your doctor first before choosing any product.

What are the Best Medicines for Arthritis Pain?

As there are hundreds of choices available in the market, choosing the best medicines for arthritis pain can be quite tricky. To help you out, here are five of the most popular and well-loved products you will find on and offline.

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Penetrex Pain Relief Therapy

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This can be one of the best medicines for arthritis pain because it contains a unique formulation called Penetrex. It is effective for alleviating arthritis-related pain, as well as carpal tunnel syndrome, golf and tennis elbow, hip pain, shin splints, back pain, and heel pain, among others.

It is easy to apply and does not result in any discomfort. It has a greaseless and stainless scent.

Active ingredients are vitamin B6, arnica, pyridoxine, MSM, boswellia Serrata, glucosamine, Choline Bitartrate, and Cetyl Myristoleate. All ingredients are clinically proven.


  • Not animal tested/cruelty-free.
  • Clinically proven ingredients, so you are sure about their effectiveness.
  • Non-greasy, non-staining, vanishing scent.
  • Free of parabens and other similar ingredients.
  • Has a lot of good reviews from users on and offline.
  • Intensive relief from pain. It heals and repairs instead of just masking pain.
  • Works even for those who have undergone surgery and need pain relief.
  • Fast and efficient pain relief.
  • Gentle and safe, but strong on pain.


  • Some people may not like the fact that it does not have a scent.
  • May not work well for some people.

PRIMAL Joint Support & Anti-Inflammatory Joint Support Soft Capsules

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This is an all-natural product that has ingredients like turmeric, ginger, boswellia, and vitamin D. It also has Celadrin. PRIMAL likewise boasts of minerals like zinc, copper, selenium, and manganese, which are essential for natural health and protection.

It is gluten, wheat, and dairy-free; and does not contain artificial ingredients, fillers, and binders.

PRIMAL works two ways: reducing and preventing inflammation and improving your well-being and overall health.


  • All-natural ingredients.
  • Efficiently helps you move without feeling any pain.
  • A good alternative to chondroitin and glucosamine.
  • Contains essential vitamins and minerals that help improve your general health.
  • Does not contain allergens like wheat, dairy, and gluten.


  • Might cause certain reactions to some, like shaking and itching.
  • Did not have any noticeable improvements in some people.

Aleve PM

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This is an NSAID medication that helps you get a good night’s sleep. It is formulated to offer relief from pain so that you will not suffer from sleeplessness and you will not wake up feeling all sorts of aches and pains. Aleve is an over-the-counter product, which means it is easy to find and purchase.

It contains 25 mg of diphenhydramine HCl (sleep aid) and 220 mg naproxen sodium (pain reliever). Aleve comes in an easy-open bottle.


  • Combines sleep aid and pain relief for the best sleep.
  • Help make waking up in the morning more fun.
  • Comes in an easy-to-open bottle.
  • Caplet is easy-to-swallow.
  • A good antidote for stress as it helps you relax.


  • Sleep aid may not work for some people.
  • Might have some negative/side effects, such as stomach bleeding.

Aleve Easy Open Arthritis Caplets

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This NSAID can be one of the best medicines for arthritis pain because it is ideal for treating minor arthritis pain and is even recommended by doctors. According to some sources, it is also tougher (more effective) than Tylenol 8hr. Aleve Easy Open’s effect can last for at least 12 hours. Its major ingredient is 220 mg of naproxen sodium. Just one capsule a day can already help relieve pain caused by arthritis.

Aside from arthritic pain, this can also help alleviate aches and pains related to a backache, headache, toothache, muscular aches, and menstrual cramps.


  • Helps relieve a variety of symptoms.
  • Has a 12-hour effect.
  • Said to be stronger and more efficient than even the leading brand.
  • One capsule or caplet is all you need.
  • Easy-to-swallow caplets.
  • Long shelf life.


  • May cause nausea and stomach ulcers.

Biofreeze Pain Relief Gel for Arthritis

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This is a roll-on cold, topical analgesic that has a cooling effect. It is recommended by physical therapists, chiropractors, athletic trainers, and massage therapists, among others. Its primary function is to relieve pain caused by arthritis and other similar conditions. Biofreeze is NSAID-free and does not have propylene glycol and parabens.

It is a fast-acting topical analgesic formulated with the best quality ingredients. It is also easy to apply; and when it is applied, it penetrates deeply. Its effect is long lasting.


  • No parabens and propylene glycol.
  • Provides immediate pain relief.
  • NSAID-free and proven effective through clinical research.
  • Penetrates quickly and deeply on painful joints, sore muscles, sprains, and even on bruises and strains.
  • Can be used on all body parts.
  • Easy-to-use and comes in a good, practical size.


  • May not be strong enough for some people.

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Our Choice for the Best Medicine for Arthritis Pain

Choosing the best medicines for arthritis pain is not easy as the products on this list have quite the same advantages and disadvantages. However, among the five, the one that has the best effect is Penetrex Pain Relief Therapy. It may not be as strong as Aleve or as popular as the other brands on the list, but it works effectively and efficiently.

One of the things that make this a strong contender for the best medicines for arthritis pain is the fact that it does not contain complicated ingredients, the ones that are difficult to read. This gives us a guarantee that applying the medication will not cause any harm or adverse reactions.

Additionally, the product is not difficult to use. In fact, it can be applied in a matter of seconds. Moreover, after a few minutes, you will already feel it making its way to that part of your body that is badly bruised or in pain. Moreover, it works quickly. No need to wait for hours or days.

Best of all, Penetrex Pain Relief Therapy rightfully belongs to the list of the best medicines for arthritis pain because it helps eliminate and treat the pain. Unlike other medicines that offer temporary or superficial relief, this arthritis medication does not simply hide or mask the pain. Instead, it heals and then repairs. So Penetrex offers complete relief and healing from whatever arthritis pain that may be hounding you.

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