Is Combiflam Syrup Safe for Baby?


When your baby is down with fever or pain and cries, you are very concerned regarding this unpleasant episode. You postpone all activities to mitigate the suffering of your baby.  Fever and pain are frequent in infants and children of all ages and represents more than 30% of all the complaints referred to paediatricians. Combiflam uses are very much prevalent as an OTC, NSAID and pain reliever.

It is well known that fever is part of the body’s natural response to an infection and inflammation or immunological disorders. Apart from Combiflam, Cheston cold helps in providing relief from running nose, sneezing and hives. The latter is an antihistamine that reduces the effect of chemicals in the body.

Pediatric pain is mainly experienced in association with an illness or injury, and there is a growing concern about its potential adverse effects on the developing brain.

The first thing that comes to your mind is to find an immediate solution to mitigate the suffering of your baby. Your family or friends may tell you about Combiflam uses. You try trusted home remedies to bring much-needed pain relief to your progeny, asking your experienced mother or other elders in the family, pain management methods they had adopted during such a crisis.

Medical consultants, start the treatment of pain in a much planned manner, after reviewing the medical records (previous prescriptions, laboratory test findings, present health concerns and health condition starting each analgesic carefully according to the response and development of side effects.

If one drug’s action is not efficacious and the pain is not relieved, even after giving a higher dose a critical review of the case is done before, changing the drug.

Do not use aspirin to treat your child’s fever or pain, pain, as aspirin has been linked to liver failure.

Pediatric pain or pain experienced by children might be under-recognised and consequently undertreated. In line with pediatric guidelines, doctors recommend the use of paracetamol or acetaminophen as the first line drug for treating fever and mild to moderate pain. The route of administration, e.g. oral or intravenous or rectal is not appropriate in some cases. Many nurses and parents preferred rectal administration over the recommended oral administration.

Optimal efficacy and safety can be achieved with an oral dose of 15mg/kg body weight every 6 hours. A recent study has identified that paracetamol is one of the four medications most frequently involved in pediatric overdosing.

Medical evidence supports the use of Ibuprofen and paracetamol combination syrup (Combiflam uses ) over narcotic drugs which are used to alleviate the pain but are habit forming and often misused.

A Paracetamol and Ibuprofen combination (Combiflam syrup uses) is a time-tested anti-inflammatory, analgesic and antipyretic used by thousands of patients. Combiflam syrup 60 ml is a product manufactured by the world renowned pharmaceutical firm, Sanofi Aventis.

Combiflam Syrup is a combination of Ibuprofen 100mg per 5 ml and acetaminophen/paracetamol 162.5 mg as active ingredients.

Certain types of moderate-severe pain, combining ibuprofen and paracetamol/acetaminophen offers.

Although acetaminophen/paracetamol is used widely, research is still being done to find out, how this drug works, which is different from non-steroidal anti-inflammatory drugs.

Research points to a mechanism of pain connected to the brain, having minimal inflammatory activity. Although the majority of the medical professional, seek an anti-inflammatory and analgesic, which is safe, very effective in ameliorating the pain and fever and providing much-related relief to the patient in the shortest possible time.

Comparative studies have shown that Ibuprofen and paracetamol combinations( Combiflam uses) offer similar pain relief to that of codeine-based painkillers in severe pain, with tolerability improved generally

Combiflam syrup 60 ml is safe to be administered to baby patients six months and above till the adult age. There are no established research studies to show the efficacy and safety of Combiflam uses, for newborn babies till the age of 6 months.

Treatment with Combiflam Syrup 60 ml

Combiflam uses for the treatment of the following adverse medical conditions are well established:

Fever, ear pain, cold and influenza, toothache, joints pain, muscle pain, back pain, headache, neuropathic pain, painful periods, arthritis and soft tissue injuries.

It is important to follow the manufacturers instructions on the mode of administration of Combiflam to your baby if you are purchasing a bottle from a pharmacy to alleviate acute pain at that instant.

When to Take Your Baby to an Emergency Department of a Hospital

It is always advisable to take medical consultation from a hospital emergency doctor, to be sure of a safe and effective treatment in the following situations:-

  • The child is younger than six months (regardless of prematurity).
  • You are not able to contact your child’s regular paediatrician.
  • The OTC medicine you gave the child is unable to control the fever and associated pain.
  • If you suspect the child to have become dehydrated from vomiting, diarrhoea, if your child is not drinking water or milk, has sunken eyes, dry diapers, tented skin, cannot be roused and is not responding to your words.
  • You may have taken the child to a doctor, come back home and after some time, the condition of your child gets worse, or new symptoms develop, necessitating immediate travel to the emergency department of a hospital or a paediatricians clinic.
  • A seizure occurs.
  • You observe that your child’s breathing is shallow, rapid or feeling difficulty in breathing.
  • The child has complex medical problems and takes prescription medicines on a chronic basis.

After arriving at the emergency department of a hospital, a nurse or healthcare assistant will assess the severity of the problem of the child and decides how quickly a doctor has to attend to your child.

The nurses or paramedical staffs are well trained and experienced. The nurse will take your child to the emergency room if a life-threatening situation is apparent.

Dosage and Frequency, Combiflam Uses

You should not exceed the dose and the frequency of administration, keeping a strict vigil on the baby’s activity since babies may not be able to tell you their medical complaints at this age, any unusual activity may prove to be detrimental to the baby’s health.

Take your baby immediately to a hospital or call an ambulance. The dose of Combiflam syrup is usually 10 to 15 mg/Kg body weight, to be given every 4 to 6 hours.

The pain relief may be experienced within 30 to 60 minutes of administering the medicine. Keep a constant watch on your baby during this period.

Safety Advice

When you buy Combiflam syrup over the counter especially for your baby or kid, this may be done only in an emergency. Combiflam uses in children should preferably be monitored very strictly.

As any medicine can exhibit adverse effects, to avert any untoward incident it is always advisable to consult a Pediatrician or your GP, who will diagnose the cause of this ailment and prescribe medicines which are safe for your child.

Side Effects of Combiflam Use

The following side effects may be experienced in a patient who has been given a combiflam suspension. Combiflam syrup (ibuprofen+paracetamol) is safe to a large extent in babies or children over six months if the dosage and duration of the medicine are strictly adhered to.

A few side effects may be experienced by the patient, although it may not be the same for all patients. The side effects may be mild or very serious, so this medicine should always be given to a patient in consultation with a doctor.

Thrombocytopenia, vision disturbance, agranulocytosis, allergies, skin rashes, eczema, asthma, complications of the liver, abnormal blood counts, high blood pressure, bleeding from the nose, stroke, heart attack.

Gastrointestinal complications, nausea and vomiting, hemorrhage abdominal pain, indigestion, hyperacidity, breathlessness, weakness, malaise, urinary tract problems, sour stomach, heartburn, constipation, decreased urine output  may happen.

Yellow coloured eyes or skin, skin, ringing or buzzing in the ear, nervousness, loss of appetite may take place.

Combiflam syrup is not recommended for known patients of asthma, allergic- rhinitis, urticaria, gastrointestinal bleeding, and nervousness.

Doctor’s advice on Combiflam use, should not be for more than a few days at a time. Unless medically advised, in which cases condition of the patient is to be reviewed regularly by the doctor to mitigate any serious complications.

Drug Interactions with Combiflam Syrup

Inform the Pediatrician or GP who is treating your child about all the prescription medicines, over the counter medicines, herbal supplements your child has taken in the past.

The patient’s medical history will guide the doctor in his decision making to prescribe the right medications which are safe and effective. This procedure has to be adopted to avoid any further unpleasant effects your child has to bear.

Combiflam uses, may cause some major drug interactions which a patient is already taking like- aspirin, corticosteroids, cyclosporine, ketoconazole, leflunomide, lithium drugs methotrexate, cardiac glycosides, digoxin, blood pressure medication, cholestyramine, diuretics, isoniazid, blood sugar lowering medicines.

Also, drugs like metoclopramide, domperidone, baclofen, probenecid other NSAID’s, quinolone antibiotics, tacrolimus, zidovudine should be avoided. Your doctor may perform periodic liver and kidney function test to assess any untoward effect, like possible gastrointestinal bleeding, which may develop on Combiflam uses to your child.

In a nutshell, Combiflam uses are well-recognised worldwide as a time-tested medicine to treat fever and pain. This combination is widely prescribed by pediatricians and general physicians. Look out for kid friendly anti inflammatory recipes here.

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